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Weight Trajectory : Assess if weight loss is ongoing or plateaued to determine the stability of pelvic soft-tissue volume

Some pointed to evidence suggesting that not everyone diagnosed with obesity needs to lose weight to stay healthy and bemoaned the use of BMI, a controversial measure that is increasingly considered inadequate unless additional factors such as waist circumference are also evaluated

DR is one of the most frequent complications of DM and the leading cause of blindness in the adult population [54]

The Bottom Line Interest in next-generation weight-loss drugs like retatrutide will likely continue to grow

Body composition, not the drug alone, determines the outcome

However, it can be legally sold and purchased as a research chemical for legitimate research purposes